Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet
Jeff S. Volek; Stephen D. Phinney; Cassandra E. Forsythe; Erin E. Quann; Richard J. Wood; Michael J. Puglisi; William J. Kraemer; Doug M. Bibus; Maria Luz Fernandez; Richard D. FeinmanRCT with 40 participants: Both interventions led to improvements in several metabolic markers, but subjects following the CRD had consistently reduced glucose (-12%) and insulin (-50%) concentrations, insulin sensitivity (-55%), weight loss (-10%), decreased adiposity (-14%), and more favorable triacylglycerol (TAG) (-51%), HDL-C (13%) and total cholesterol/HDL-C ratio (-14%) responses. In addition to these markers for…
Read More >>Comparative Study of the Effects of a 1-Year Dietary Intervention of a Low-Carbohydrate Diet Versus a Low-Fat Diet on Weight and Glycemic Control in Type 2 Diabetes
Nichola J. Davis, MD, MS; Nora Tomuta, MD; Clyde Schechter, MD; Carmen R. Isasi, MD, PHD; C.J. Segal-Isaacson, EDD, RD; Daniel Stein, MD; Joel Zonszein, MD; Judith Wylie-Rosett, EDD, RDRCT with 105 participants: Among patients with type 2 diabetes, after 1 year a lowcarbohydrate diet had effects on weight and A1C similar to those seen with a low-fat diet. There was no significant effect on blood pressure, but the low-carbohydrate diet produced a greater increase in HDL cholesterol. Weight loss occurred faster in the low-carbohydrate…
Read More >>Effects of a Low-intensity Intervention That Prescribed a Low Carbohydrate vs. a Low Fat Diet in Obese, Diabetic Participants
Nayyar Iqbal; Marion L. Vetter; Reneé H. Moore; Jesse L. Chittams; Cornelia V. Dalton‐Bakes; Monique Dowd; Catherine Williams‐Smith; Serena Cardillo; Thomas A. WaddenRCT with 104 Participants: At this time, participants in the low-carbohydrate group lost 1.5 kg, compared to 0.2 kg in the low-fat group (P = 0.147). Lipids, glycemic indexes, and dietary intake did not differ between groups at month 24 (or at months 6 or 12).
Read More >>Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes
Talib A. Hussain, M.B., Ch.B., R.C.G.P.; Thazhumpal C. Mathew, M.Sc., Ph.D., F.R.C.Path.; Ali A. Dashti, M.Sc., Ph.D.; Sami Asfar, M.B., Ch.B., M.D., F.R.C.S., F.A.C.S.; Naji Al-Zaid, B.Sc., Ph.D.; Hussein M. Dashti, M.D., Ph.D., F.I.C.S., F.A.C.S.Non-randomized 2 arm prospective with 363 participants: This study shows the beneficial effects of a ketogenic diet over the conventional LCD in obese diabetic subjects. The ketogenic diet appears to improve glycemic control. Therefore, diabetic patients on a ketogenic diet should be under strict medical supervision because the LCKD can significantly lower blood glucose levels.
Read More >>Systematic review and meta-analysis of different dietary approaches to the management of type 2 diabetes
Olubukola Ajala, Patrick English, Jonathan PinkneyLow-carbohydrate are as effective as low-GI, Mediterranean, and high protein diets in improving various markers of cardiovascular risk in people with diabetes and should be considered in the overall strategy of diabetes management.
Read More >>A Non-calorie-restricted Low-carbohydrate Diet is Effective as an Alternative Therapy for Patients with Type 2 Diabetes
Yoshifumi Yamada, Junichi Uchida, Hisa Izumi, Yoko Tsukamoto, Gaku Inoue, Yuichi Watanabe, Junichiro Irie, Satoru YamadaRCT with 24 participants. Findings suggest that a low-carbohydrate diet is effective in lowering the HbA1c and triglyceride levels in patients with type 2 diabetes who are unable to adhere to a calorie restricted diet.
Read More >>A Very Low Carbohydrate, Low Saturated Fat Diet for Type 2 Diabetes Management: A Randomized Trial
Jeannie Tay, Natalie D. Luscombe-Marsh, Campbell H. Thompson, Manny Noakes, Jon D. Buckley, Gary A. Wittert, William S. Yancy Jr., Grant D. BrinkworthRCT with 93 participants. Both diets achieved substantial improvements for several clinical glycemic control and CVD risk markers. These improvements and reductions in GV and anti-glycemic medication requirements were greatest with the LC compared with HC. This suggests an LC diet with low saturated fat may be an effective dietary approach for T2DM management if…
Read More >>A Randomized Pilot Trial of a Moderate Carbohydrate Diet Compared to a Very Low Carbohydrate Diet in Overweight or Obese Individuals with Type 2 Diabetes Mellitus or Prediabetes
Laura R. Saslow, Sarah Kim, Jennifer J. Daubenmier, Judith T. Moskowitz, Stephen D. Phinney, Veronica Goldman, Elizabeth J. Murphy, Rachel M. Cox, Patricia Moran, Fredrick M. HechtRCT with 34 participants. Results suggest that a very low carbohydrate diet coupled with skills to promote behavior change may improve glycemic control in type 2 diabetes while allowing decreases in diabetes medications.
Read More >>Retrospective Study on the Efficacy of a Low- Carbohydrate Diet for Impaired Glucose Tolerance
Satoshi Maekawa, Tetsuya Kawahara, Ryosuke Nomura, Takayuki Murase, Yasuyoshi Ann, Masayuki Oeholm, Masaru Harada2 Arm Retrospective with 72 participants: The LCD is effective for normalizing blood glucose and preventing progression to type-2 diabetes in patients with Impaired Glucose Tolerance.
Read More >>Advice to follow a low-carbohydrate diet has a favourable impact on low-grade inflammation in type 2 diabetes compared with advice to follow a low-fat diet
Lena Jonasson, Hans Guldbrand, Anna K. Lundberg, Fredrik H. NystromRCT with 61 Participants. Low Carbohydrate Diet was found significantly to improve the sub-clinical inflammatory state in type 2 diabetes.
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